Elaine Binkley, MD
Contact information
LOCATION
SPECIALTY
Ophthalmic Oncologist
Education and Fellowships
-MEDICAL SCHOOL
The Ohio State University College of Medicine
-RESIDENCY
The Ohio State University Havener Eye Institute
-FELLOWSHIP
University of Iowa Department of Ophthalmology and Visual Sciences
-FELLOWSHIP
University of Iowa Department of Ophthalmology and Visual Sciences
BOARD CERTIFICATIONS
American Board of Ophthalmology
Current Positions
Assistant Professor
LOCATION
- University of Iowa Department of Ophthalmology and Visual Sciences
200 Hawkins Drive, Iowa City, IA 52242
Map and directions »
SPECIALTY
Ophthalmic Oncologist
Education and Fellowships
-MEDICAL SCHOOL
The Ohio State University College of Medicine
-RESIDENCY
The Ohio State University Havener Eye Institute
-FELLOWSHIP
University of Iowa Department of Ophthalmology and Visual Sciences
-FELLOWSHIP
University of Iowa Department of Ophthalmology and Visual Sciences
BOARD CERTIFICATIONS
American Board of Ophthalmology
Current Positions
Assistant Professor
Biography
Elaine M. Binkley, M.D.
April 2020
I. EDUCATIONAL AND PROFESSIONAL HISTORY
A. Education, Certification, and Licensure
1. Undergraduate and Postgraduate Medical Education
9/2003 – 5/2007 Denison University, Granville, OH
B.S. Biology
Summa Cum Laude, Co-Valedictorian
8/2007 – 6/2011 The Ohio State University College of Medicine, Columbus, OH
Doctor of Medicine – Magna Cum Laude
6/2011 – 6/2012 Riverside Methodist Hospital, Columbus, OH
Transitional Internship
7/2012 – 6/2015 The Ohio State University Wexner Medical Center, Columbus, OH
Ophthalmology Residency
7/2015 – 6/2017 University of Iowa, Iowa City, IA
Vitreoretinal Surgery Fellowship
7/2017 – 6/2018 University of Iowa, Iowa City, IA
Retina Clinical and Molecular Research Fellowship
One year fellowship with clinical emphasis on ocular oncology and inherited retinal diseases
7/2018 – 12/2018 Cleveland Clinic Cole Eye Institute, Cleveland, OH
Ocular oncology consultant
2. Certification
11/6/16 American Board of Ophthalmology
3. Licensure
Iowa 42423 Expires: 9/1/2020
B. Professional and Academic Positions Held
2/1/2019-present Assistant Professor, University of Iowa Department of Ophthalmology and Visual Sciences, Vitreoretinal Surgery/Ocular Oncology, Iowa City, IA
C. Honors, Awards, Recognitions, Outstanding Achievements
2006 Phi Beta Kappa: Junior inductee
2007 Denison University President’s Medal recipient: Denison University Academic Award
2007 Denison University Biology Department Senior Fellow
2008 Phi Kappa Phi Honor Society
2009 (Inducted) Landacre Honor Society (Ohio State University College of Medicine Research Honor Society
2010 Alpha Omega Alpha Honor Medical Society: Junior inductee
2012 Transitional Year Intern of the Year-Riverside Methodist Hospital
2013 First place OSU Department of Ophthalmology Resident Research Day
2014 First place OSU Department of Ophthalmology Resident Research Day
2015 Inducted into OSU Gold Humanism Honor Society Resident Chapter
2014-2015 Ohio State University Department of Ophthalmology Chief Resident
2017 VitreoRetinal Surgery Foundation Research Award
2018 P.J. Leinfelder Award-University of Iowa Department of Ophthalmology Research Award
2018 Fellow Teaching Award-University of Iowa Department of Ophthalmology
II. Teaching
A. Teaching Assignments
2/25/19 Morning Rounds-Department of Ophthalmology, University of Iowa
3/18/19 Intern On-Call Safety Lunch-Department of Ophthalmology, University of Iowa
5/24/19 Medical Student Lecture-Department of Ophthalmology, University of Iowa
10/21/19 Ophthalmology Intern Safety Lunch Series-Retinal detachment-Department of Ophthalmology University of Iowa
1/17/20 BCSC Resident Lecture Series – Retinoblastoma, Melanoma, Department of Ophthalmology, University of Iowa (2 hours)
2/17/20 Ophthalmology Intern Lunch Lecture Series, Posterior Vitreous Detachment, Department of Ophthalmology University of Iowa
3/4/20 OKAP Resident Review Series – Ocular Tumors, Department of Ophthalmology, University of Iowa
B. Clinical Teaching
2/2019-present Staff Vitreoretinal Clinic/Ocular Oncology clinic 2 days per week year round
2/2019-present Perform Vitreoretinal Surgical and Ocular Oncology Procedures 1 day every other week year-round, additional cases as needed
III. SCHOLARSHIP/PROFESSIONAL PRODUCTIVITY
A. Publications or creative works – Peer-reviewed papers
1. Walters J, Binkley E, Haygood R, Romano L: Evolutionary analysis of the cis-regulatory region of the spicule matrix gene SM50 in strongylocentrotid sea urchins. Developmental Biology 2008,.315(2):567-578. PMID: 18262514.
2. Mundy-Bosse B, Young G, Bauer T, Binkley E, Bloomston M, Bill M, Bekaii-Saab T, Carson W, 3rd, Lesinski G: Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4(+) T cells from patients with GI malignancy. Cancer Immunology, Immunotherapy. 2011. 60(9):1269-1279. PMID: 21604071.
3. Fonkem E, Skordilis M, Binkley E, Raymer D. Epstein A, Arnold D, Kissel J, Lawson V: Ethambutol toxicity exacerbating the phenotype of CMT2A2. Muscle & Nerve. 2013. 48(1):140- 144. PMID: 23733358.
4. Cebulla C, Binkley E, Pilarski R, Massengill J, Rai K, Liebner D, Marino M, Singh A, Abdel- Rahman M: Analysis of BAP1 germline gene mutation in young uveal melanoma patients. Ophthalmic Genetics. 2015. 17:1-6. PMID: 25687217.
5. Velez G, Roybal C, Binkley E, Bassuk A, Tsang S, Mahajan V: Proteomic analysis of elevated intraocular pressure and retinal detachment. Am J Ophthalmol. 2017. April (5):107-110. PMID: 28825049.
6. Carballo J, Binkley E, Han I, Dowden A: Intraoperative anaphylaxis to bacitracin during scleral buckle surgery. Annals of Allergy, Asthma, and Immunology. 2017. 119(6):559-560. PMID: 29042173.
7. Boldt HC, Binkley E: Treating small choroidal melanomas: smaller is better. JAMA Ophthalmology. 2018. 136(12):1333-1334. PMID: 30267041.
8. Bellerive C, Binkley E, Singh AD: Class 2 gene expression profile of a hemorrhagic pigment epithelial detachment misdiagnosed as melanoma. Ophthalmology Retina. 2019. 3(5):453-455. PMID: 31044741.
9. Davanzo J, Binkley E, Bena J, Singh AD: Risk-stratified systemic surveillance in uveal melanoma. British Journal of Ophthalmology. 2019. 103(12):1868-1871. PMID 30705044.
10. Kunkler AL, Binkley EM, Mantopoulos D, Hendershot AJ, Ohr MP, Kendra KL, Davidorf FH, Cebulla CM: Known and novel ocular toxicities of biologics, targeted agents, and traditional chemotherapeutics. Graefe’s Arch Exp Ophthalmol. 2019. 257(8):1771-1781. PMID: 3108752.
11. Binkley E, Triozzi PL, Rybicki L, Acherger S, Aldrich W, Singh A: A prospective trial of adjuvant therapy for high-risk uveal melanoma: assessing 5-year survival outcomes. Br J Ophthalmol.. 2020. 104(4)524-528.
12. Wiley LA, Binkley EM, DeLuca AP, Workalemanhu G, Tatro NJ, Luse MA, Kennedy EL, Folk JC, Scheetz TE, Ballas ZK, Tucker BA, Mullins RF, Han IC, Stone EM: Autoimmune retinopathy mimicking heritable retinal degeneration in a patient with common variable immune deficiency. Retina Cases Brief Rep. 2019..[Epub ahead of print]. PMID 31764884.
13. Boldt HC, Murray T, Binkley E. Studies evaluating visual outcomes after brachytherapy in uveal melanoma: strengths and limitations of current investigations. JAMA Ophthalmol. 2019 Dec 12. Doi: 10.1001/jamaophthamol.2019.5122. PMID 31830236
14. Voigt AP, Binkley E, Flamme-Wiese MJ, Zeng S, DeLuca A, Scheetz, TE, Tucker BA, Mullins RF, and Stone EM. Single-cell RNA sequencing in human retinal degeneration reveals distinct glial cell populations. Cells 2020 9(2) 438. PMID 32069977.
15. Binkley E, Biscotti C, Singh A, Sears J, Singh AD, Narala R, Mruthyunjaya P. Diagnostic and therapeutic challenges. Retina 2020. [epub ahead of print]. PMID 32134803.
16. Binkley E, Bena J, Davanzo J, Hinz C, Boldt HC, Singh AD. GEP prognostication in posterior uveal melanoma: does size matter? Ophthalmol Retina 2020. [epub ahead of print]. PMID 32081600.
Submitted Manuscripts
1. Binkley E, Sampson A, Syed N, Boldt HC. Metastatic squamous cell carcinoma of the tonsil mimicking choroidal melanoma. Submitted to Retina Cases and Brief Reports.
Book Chapters
1. Binkley E, Traboulsi E, Singh A. Neuro-oculocutaneous syndromes (phakomatoses). In: Singh AD, Damato BE (Eds.), Clinical Ophthalmic Oncology – Retinal Tumors 3rd Edition. Switzerland: Springer International Publishing, 2019:115-145.
2. Binkley E, Wiley L. Cancer Genetics. In: Singh AD, Damato BE (Eds.), Clinical Ophthalmic Oncology – Basic Principles 3rd Edition. Switzerland: Springer International Publishing, 2019:79-86.
3. Yang J, Binkley E, Singh AD, Carvajal R. Uveal melanoma: adjuvant therapy. In: Damato BE, Singh AD (Eds.), Clinical Ophthalmic Oncology–Uveal Tumors 3rd Edition. Switzerland: Springer International Publishing, 2019: 305-315.
4. Binkley E, Leskov I, Singh AD. Bilateral diffuse uveal melanocytic proliferation. In: Damato BE, Singh AD (Eds.), Clinical Ophthalmic Oncology–Uveal Tumors 3rd Edition. Switzerland: Springer International Publishing, 2019: 441-446.
5. Binkley E, Schachat A. Leukemias, chapter 358. To be published in Albert & Jakobiec’s Principles and Practice of Ophthalmology-Ocular Oncology Section, 4th edition. IN PRESS
6. King B, Binkley E, Boldt HC. Tumor involvement of the vitreous, chapter 364. To be published in Albert & Jakobiec’s Principles and Practice of Ophthalmology-Ocular Oncology Section, 4th edition. IN PRESS
7. Binkley E, Traboulsi E, Singh AD. The Phakomatoses, chapter 366. To be published in Albert & Jakobiec’s Principles and Practice of Ophthalmology-Ocular Oncology Section, 4th edition. IN PRESS
Abstracts
1. Walters J, Binkley E, Haygood R, Romano L: Evolutionary analysis of the cis-regulatory region of SM50, a gene that is essential for skeletogenesis in the sea urchin. Society for Developmental Biology Meeting, 2006.
2. Kim B, Kusibati R, Binkley E, Godbout J, Fisher A, Cebulla C: Effect of posterior segment components on BV-2 microglial cell M1/M2 polarization. ARVO Annual Meeting, Seattle, WA, May 2013.
3. Binkley E, Cebulla C, Pilarski R, Massengilll J, Marino M, Singh A, Abdel-Rahman M: Lack of BAP1 germline gene mutation in patients with early onset uveal melanoma. ARVO Annual Meeting, Orlando, FL, May 2014.
4. Kunkler A, Binkley E, Mantopoulos D, Kendra K, Cebulla C: Ocular side effects of traditional chemotherapeutics and small molecule inhibitors. ARVO Annual Meeting, Seattle, WA, May 2016.
5. Mantopoulos D, Binkley E, Kunkler A, Kendra K, Cebulla C: Chemotherapy with biological agents and ocular side effects. ARVO Annual Meeting, Seattle, WA, May 2016.
6. Watson J, Carey A, Binkley E, Boldt H, Folk J, Sohn E, Mahajan V, Gehrs K, Russell S: Long-term follow-up of ocular histoplasmosis in the anti-VEGF era. ARVO Annual Meeting, Seattle, WA, May 2016.
7. Binkley E, Watson J, Russell S, Mahajan V, Boldt H, Folk J, Abramoff M, Gehrs K, Sohn E: Disease recurrence following endophthalmitis associated with intravitreal injection. ARVO Annual Meeting, Seattle, WA, May 2016.
8. Folk J, Binkley E: Late onset severe visual field loss in patients with retina vasculitis. 9th International Symposium on Uveitis, Dublin, Ireland, August 2016.
9. Binkley E, Critser D, Han I, Abramoff M, Folk J: Imaging vitreous cell using cirrus OCT. American Academy of Ophthalmology Annual Meeting, New Orleans, LA, November 2017.
10. Xiao C, Binkley E, Rexach J, Knight-Johnson A, Khemani P, Fogel B, Das S, Stone E, Gomez C: A family with spinocerebellar ataxia and retinitis pigmentosa related to a novel ELOVL4 mutation. American Academy of Neurology Annual Meeting, Los Angeles, CA, April 2018.
11. Feiler DL, Han IC, Binkley EM, Critser B, Folk JC: Automated posterior vitreous inflammation measurement using OCT. American Academy of Ophthalmology Annual Meeting, Chicago, IL, October 2018.
12. Davanzo J, Binkley E, Bena J, Singh AD: Risk stratified systemic surveillance in uveal melanoma. E-poster at International Society for Ocular Oncology Meeting, Los Angeles, CA, March 2019.
13. Binkley E, Biscotti C, Singh A, Sears J, Singh AD: Conservative management of ciliary body mass with associated ocular inflammation. Free paper oral presentation at International Society for Ocular Oncology Meeting, Los Angeles, CA, March 2019.
14. Binkley E, Triozzi P, Rybicki L. Achberger S, Aldrich W, Singh AD: Adjuvant therapy for high risk uveal melanoma: assessing five-year survival outcomes. Free paper oral presentation at International Society for Ocular Oncology Meeting, Los Angeles, CA, March 2019.
B. Areas of Research Interest and Current Projects
My primary research focus is tumors of the posterior segment with an emphasis on posterior uveal melanoma and retinal vascular tumors (Von Hippel Lindau Disease). I am reviewing the clinical data for patients treated at UIHC for posterior uveal melanoma and am working on projects studying the clinical, molecular, and imaging features of radiation retinopathy. I am working on a project with Dr. Budd Tucker studying the mechanisms behind phenotypic variability in Von Hippel Lindau disease and potential molecular treatment approaches. I am collaborating with researchers at the Cleveland Clinic for a study of potential biomarkers of metastatic disease in uveal melanoma.
IV. SERVICE
A. Memberships in Professional Organizations
American Academy of Ophthalmology
American Society of Retina Specialists
International Society for Ocular Oncology
Vit-Buckle Society
Elaine M. Binkley, M.D.
April 2020
I. EDUCATIONAL AND PROFESSIONAL HISTORY
A. Education, Certification, and Licensure
1. Undergraduate and Postgraduate Medical Education
9/2003 – 5/2007 Denison University, Granville, OH
B.S. Biology
Summa Cum Laude, Co-Valedictorian
8/2007 – 6/2011 The Ohio State University College of Medicine, Columbus, OH
Doctor of Medicine – Magna Cum Laude
6/2011 – 6/2012 Riverside Methodist Hospital, Columbus, OH
Transitional Internship
7/2012 – 6/2015 The Ohio State University Wexner Medical Center, Columbus, OH
Ophthalmology Residency
7/2015 – 6/2017 University of Iowa, Iowa City, IA
Vitreoretinal Surgery Fellowship
7/2017 – 6/2018 University of Iowa, Iowa City, IA
Retina Clinical and Molecular Research Fellowship
One year fellowship with clinical emphasis on ocular oncology and inherited retinal diseases
7/2018 – 12/2018 Cleveland Clinic Cole Eye Institute, Cleveland, OH
Ocular oncology consultant
2. Certification
11/6/16 American Board of Ophthalmology
3. Licensure
Iowa 42423 Expires: 9/1/2020
B. Professional and Academic Positions Held
2/1/2019-present Assistant Professor, University of Iowa Department of Ophthalmology and Visual Sciences, Vitreoretinal Surgery/Ocular Oncology, Iowa City, IA
C. Honors, Awards, Recognitions, Outstanding Achievements
2006 Phi Beta Kappa: Junior inductee
2007 Denison University President’s Medal recipient: Denison University Academic Award
2007 Denison University Biology Department Senior Fellow
2008 Phi Kappa Phi Honor Society
2009 (Inducted) Landacre Honor Society (Ohio State University College of Medicine Research Honor Society
2010 Alpha Omega Alpha Honor Medical Society: Junior inductee
2012 Transitional Year Intern of the Year-Riverside Methodist Hospital
2013 First place OSU Department of Ophthalmology Resident Research Day
2014 First place OSU Department of Ophthalmology Resident Research Day
2015 Inducted into OSU Gold Humanism Honor Society Resident Chapter
2014-2015 Ohio State University Department of Ophthalmology Chief Resident
2017 VitreoRetinal Surgery Foundation Research Award
2018 P.J. Leinfelder Award-University of Iowa Department of Ophthalmology Research Award
2018 Fellow Teaching Award-University of Iowa Department of Ophthalmology
II. Teaching
A. Teaching Assignments
2/25/19 Morning Rounds-Department of Ophthalmology, University of Iowa
3/18/19 Intern On-Call Safety Lunch-Department of Ophthalmology, University of Iowa
5/24/19 Medical Student Lecture-Department of Ophthalmology, University of Iowa
10/21/19 Ophthalmology Intern Safety Lunch Series-Retinal detachment-Department of Ophthalmology University of Iowa
1/17/20 BCSC Resident Lecture Series – Retinoblastoma, Melanoma, Department of Ophthalmology, University of Iowa (2 hours)
2/17/20 Ophthalmology Intern Lunch Lecture Series, Posterior Vitreous Detachment, Department of Ophthalmology University of Iowa
3/4/20 OKAP Resident Review Series – Ocular Tumors, Department of Ophthalmology, University of Iowa
B. Clinical Teaching
2/2019-present Staff Vitreoretinal Clinic/Ocular Oncology clinic 2 days per week year round
2/2019-present Perform Vitreoretinal Surgical and Ocular Oncology Procedures 1 day every other week year-round, additional cases as needed
III. SCHOLARSHIP/PROFESSIONAL PRODUCTIVITY
A. Publications or creative works – Peer-reviewed papers
1. Walters J, Binkley E, Haygood R, Romano L: Evolutionary analysis of the cis-regulatory region of the spicule matrix gene SM50 in strongylocentrotid sea urchins. Developmental Biology 2008,.315(2):567-578. PMID: 18262514.
2. Mundy-Bosse B, Young G, Bauer T, Binkley E, Bloomston M, Bill M, Bekaii-Saab T, Carson W, 3rd, Lesinski G: Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4(+) T cells from patients with GI malignancy. Cancer Immunology, Immunotherapy. 2011. 60(9):1269-1279. PMID: 21604071.
3. Fonkem E, Skordilis M, Binkley E, Raymer D. Epstein A, Arnold D, Kissel J, Lawson V: Ethambutol toxicity exacerbating the phenotype of CMT2A2. Muscle & Nerve. 2013. 48(1):140- 144. PMID: 23733358.
4. Cebulla C, Binkley E, Pilarski R, Massengill J, Rai K, Liebner D, Marino M, Singh A, Abdel- Rahman M: Analysis of BAP1 germline gene mutation in young uveal melanoma patients. Ophthalmic Genetics. 2015. 17:1-6. PMID: 25687217.
5. Velez G, Roybal C, Binkley E, Bassuk A, Tsang S, Mahajan V: Proteomic analysis of elevated intraocular pressure and retinal detachment. Am J Ophthalmol. 2017. April (5):107-110. PMID: 28825049.
6. Carballo J, Binkley E, Han I, Dowden A: Intraoperative anaphylaxis to bacitracin during scleral buckle surgery. Annals of Allergy, Asthma, and Immunology. 2017. 119(6):559-560. PMID: 29042173.
7. Boldt HC, Binkley E: Treating small choroidal melanomas: smaller is better. JAMA Ophthalmology. 2018. 136(12):1333-1334. PMID: 30267041.
8. Bellerive C, Binkley E, Singh AD: Class 2 gene expression profile of a hemorrhagic pigment epithelial detachment misdiagnosed as melanoma. Ophthalmology Retina. 2019. 3(5):453-455. PMID: 31044741.
9. Davanzo J, Binkley E, Bena J, Singh AD: Risk-stratified systemic surveillance in uveal melanoma. British Journal of Ophthalmology. 2019. 103(12):1868-1871. PMID 30705044.
10. Kunkler AL, Binkley EM, Mantopoulos D, Hendershot AJ, Ohr MP, Kendra KL, Davidorf FH, Cebulla CM: Known and novel ocular toxicities of biologics, targeted agents, and traditional chemotherapeutics. Graefe’s Arch Exp Ophthalmol. 2019. 257(8):1771-1781. PMID: 3108752.
11. Binkley E, Triozzi PL, Rybicki L, Acherger S, Aldrich W, Singh A: A prospective trial of adjuvant therapy for high-risk uveal melanoma: assessing 5-year survival outcomes. Br J Ophthalmol.. 2020. 104(4)524-528.
12. Wiley LA, Binkley EM, DeLuca AP, Workalemanhu G, Tatro NJ, Luse MA, Kennedy EL, Folk JC, Scheetz TE, Ballas ZK, Tucker BA, Mullins RF, Han IC, Stone EM: Autoimmune retinopathy mimicking heritable retinal degeneration in a patient with common variable immune deficiency. Retina Cases Brief Rep. 2019..[Epub ahead of print]. PMID 31764884.
13. Boldt HC, Murray T, Binkley E. Studies evaluating visual outcomes after brachytherapy in uveal melanoma: strengths and limitations of current investigations. JAMA Ophthalmol. 2019 Dec 12. Doi: 10.1001/jamaophthamol.2019.5122. PMID 31830236
14. Voigt AP, Binkley E, Flamme-Wiese MJ, Zeng S, DeLuca A, Scheetz, TE, Tucker BA, Mullins RF, and Stone EM. Single-cell RNA sequencing in human retinal degeneration reveals distinct glial cell populations. Cells 2020 9(2) 438. PMID 32069977.
15. Binkley E, Biscotti C, Singh A, Sears J, Singh AD, Narala R, Mruthyunjaya P. Diagnostic and therapeutic challenges. Retina 2020. [epub ahead of print]. PMID 32134803.
16. Binkley E, Bena J, Davanzo J, Hinz C, Boldt HC, Singh AD. GEP prognostication in posterior uveal melanoma: does size matter? Ophthalmol Retina 2020. [epub ahead of print]. PMID 32081600.
Submitted Manuscripts
1. Binkley E, Sampson A, Syed N, Boldt HC. Metastatic squamous cell carcinoma of the tonsil mimicking choroidal melanoma. Submitted to Retina Cases and Brief Reports.
Book Chapters
1. Binkley E, Traboulsi E, Singh A. Neuro-oculocutaneous syndromes (phakomatoses). In: Singh AD, Damato BE (Eds.), Clinical Ophthalmic Oncology – Retinal Tumors 3rd Edition. Switzerland: Springer International Publishing, 2019:115-145.
2. Binkley E, Wiley L. Cancer Genetics. In: Singh AD, Damato BE (Eds.), Clinical Ophthalmic Oncology – Basic Principles 3rd Edition. Switzerland: Springer International Publishing, 2019:79-86.
3. Yang J, Binkley E, Singh AD, Carvajal R. Uveal melanoma: adjuvant therapy. In: Damato BE, Singh AD (Eds.), Clinical Ophthalmic Oncology–Uveal Tumors 3rd Edition. Switzerland: Springer International Publishing, 2019: 305-315.
4. Binkley E, Leskov I, Singh AD. Bilateral diffuse uveal melanocytic proliferation. In: Damato BE, Singh AD (Eds.), Clinical Ophthalmic Oncology–Uveal Tumors 3rd Edition. Switzerland: Springer International Publishing, 2019: 441-446.
5. Binkley E, Schachat A. Leukemias, chapter 358. To be published in Albert & Jakobiec’s Principles and Practice of Ophthalmology-Ocular Oncology Section, 4th edition. IN PRESS
6. King B, Binkley E, Boldt HC. Tumor involvement of the vitreous, chapter 364. To be published in Albert & Jakobiec’s Principles and Practice of Ophthalmology-Ocular Oncology Section, 4th edition. IN PRESS
7. Binkley E, Traboulsi E, Singh AD. The Phakomatoses, chapter 366. To be published in Albert & Jakobiec’s Principles and Practice of Ophthalmology-Ocular Oncology Section, 4th edition. IN PRESS
Abstracts
1. Walters J, Binkley E, Haygood R, Romano L: Evolutionary analysis of the cis-regulatory region of SM50, a gene that is essential for skeletogenesis in the sea urchin. Society for Developmental Biology Meeting, 2006.
2. Kim B, Kusibati R, Binkley E, Godbout J, Fisher A, Cebulla C: Effect of posterior segment components on BV-2 microglial cell M1/M2 polarization. ARVO Annual Meeting, Seattle, WA, May 2013.
3. Binkley E, Cebulla C, Pilarski R, Massengilll J, Marino M, Singh A, Abdel-Rahman M: Lack of BAP1 germline gene mutation in patients with early onset uveal melanoma. ARVO Annual Meeting, Orlando, FL, May 2014.
4. Kunkler A, Binkley E, Mantopoulos D, Kendra K, Cebulla C: Ocular side effects of traditional chemotherapeutics and small molecule inhibitors. ARVO Annual Meeting, Seattle, WA, May 2016.
5. Mantopoulos D, Binkley E, Kunkler A, Kendra K, Cebulla C: Chemotherapy with biological agents and ocular side effects. ARVO Annual Meeting, Seattle, WA, May 2016.
6. Watson J, Carey A, Binkley E, Boldt H, Folk J, Sohn E, Mahajan V, Gehrs K, Russell S: Long-term follow-up of ocular histoplasmosis in the anti-VEGF era. ARVO Annual Meeting, Seattle, WA, May 2016.
7. Binkley E, Watson J, Russell S, Mahajan V, Boldt H, Folk J, Abramoff M, Gehrs K, Sohn E: Disease recurrence following endophthalmitis associated with intravitreal injection. ARVO Annual Meeting, Seattle, WA, May 2016.
8. Folk J, Binkley E: Late onset severe visual field loss in patients with retina vasculitis. 9th International Symposium on Uveitis, Dublin, Ireland, August 2016.
9. Binkley E, Critser D, Han I, Abramoff M, Folk J: Imaging vitreous cell using cirrus OCT. American Academy of Ophthalmology Annual Meeting, New Orleans, LA, November 2017.
10. Xiao C, Binkley E, Rexach J, Knight-Johnson A, Khemani P, Fogel B, Das S, Stone E, Gomez C: A family with spinocerebellar ataxia and retinitis pigmentosa related to a novel ELOVL4 mutation. American Academy of Neurology Annual Meeting, Los Angeles, CA, April 2018.
11. Feiler DL, Han IC, Binkley EM, Critser B, Folk JC: Automated posterior vitreous inflammation measurement using OCT. American Academy of Ophthalmology Annual Meeting, Chicago, IL, October 2018.
12. Davanzo J, Binkley E, Bena J, Singh AD: Risk stratified systemic surveillance in uveal melanoma. E-poster at International Society for Ocular Oncology Meeting, Los Angeles, CA, March 2019.
13. Binkley E, Biscotti C, Singh A, Sears J, Singh AD: Conservative management of ciliary body mass with associated ocular inflammation. Free paper oral presentation at International Society for Ocular Oncology Meeting, Los Angeles, CA, March 2019.
14. Binkley E, Triozzi P, Rybicki L. Achberger S, Aldrich W, Singh AD: Adjuvant therapy for high risk uveal melanoma: assessing five-year survival outcomes. Free paper oral presentation at International Society for Ocular Oncology Meeting, Los Angeles, CA, March 2019.
B. Areas of Research Interest and Current Projects
My primary research focus is tumors of the posterior segment with an emphasis on posterior uveal melanoma and retinal vascular tumors (Von Hippel Lindau Disease). I am reviewing the clinical data for patients treated at UIHC for posterior uveal melanoma and am working on projects studying the clinical, molecular, and imaging features of radiation retinopathy. I am working on a project with Dr. Budd Tucker studying the mechanisms behind phenotypic variability in Von Hippel Lindau disease and potential molecular treatment approaches. I am collaborating with researchers at the Cleveland Clinic for a study of potential biomarkers of metastatic disease in uveal melanoma.
IV. SERVICE
A. Memberships in Professional Organizations
American Academy of Ophthalmology
American Society of Retina Specialists
International Society for Ocular Oncology
Vit-Buckle Society
Selected publications
- Analysis of BAP1 germline gene mutation in young uveal melanoma patients.
Cebulla C, Binkley E, Pilarski R, Massengill J, Rai K, Liebner D, Marino M, Singh A, Abdel-Rahman M: Analysis of BAP1 germline gene mutation in young uveal melanoma patients. Ophthalmic Genetics. 2015. 17:1-6. - Treating small choroidal melanomas: smaller is better
Boldt HC, Binkley E: Treating small choroidal melanomas: smaller is better. JAMA Ophthalmology. 2018. 136(12):1333-1334. - Class 2 gene expression profile of a hemorrhagic pigment epithelial detachment misdiagnosed as melanoma
Bellerive C, Binkley E, Singh AD: Class 2 gene expression profile of a hemorrhagic pigment epithelial detachment misdiagnosed as melanoma. Ophthalmology Retina. 2019. 3(5):453-455. - Risk-stratified systemic surveillance in uveal melanoma
Davanzo J, Binkley E, Bena J, Singh AD: Risk-stratified systemic surveillance in uveal melanoma. British Journal of Ophthalmology. 2019. 103(12).1868-1871. - Known and novel ocular toxicities of biologics, targeted agents, and traditional chemotherapeutics
Kunkler AL, Binkley EM, Mantopoulos D, Hendershot AJ, Ohr MP, Kendra KL, Davidorf FH, Cebulla CM: Known and novel ocular toxicities of biologics, targeted agents, and traditional chemotherapeutics. Graefe’s Arch Exp Ophthalmol. 2019. 257(8):1771-1781
